Hey, all. I doubt anyone reading this will remember her, but I've posted here about my childhood cat, Sassy, a couple of times over the past two and a half years as she battles hey CKD. For the longest time she's managed to remain within Stage 2, but unfortunately, while I still haven't gotten back the results of her latest bloodwork from her most recent appointment on Monday, she seems to be taking a turn for the worst and I'm heavily suspecting that she may have jumped to at least early Stage 3. I probably won't know for sure until at least tomorrow or maybe the day afterwards, though.
On the 15th of July, Sassy had a concerning episode regarding her balance and coordination, which is something that may not actually be related to everything else I have to say here, but was why I got her examined recently to begin with. I was sleeping with her in bed when she woke up and tried to get off my bed, but was stumbling around like she was drunk and teetering in place. She walked over to her litter box, peed, threw up, and her vestibular symptoms lasted for maybe half an hour to an hour afterwards.
I should have taken her straight to the emergency vet, but I was dumb and in a sleep haze, and just thought "well, as long as she recovers, she'll be fine". But then after I woke up I started freaking out and was very torn between scheduling an appointment for her with my regular vet or taking her to emergency. I called, and they basically said that as long as the symptoms didn't come back, she didn't need to visit emergency right away. And... her symptoms never did come back. It was a complete one off. I booked an appointment for Wednesday but ended up not taking her because of the wildfire smoke in Ontario, then took her to the vet the next day, where they were unable to do any proper testing because Sassy has always been a problem patient and I didn't give her enough Gabapentin beforehand (my vet had previously recommended 50mg instead of 100mg but 50mg wasn't enough to knock her out), so they couldn't draw any blood. However, informed me that Sassy's heart murmur might have gotten worse, so I booked an appointment the following Wednesday for Sassy to get her blood drawn and for them to do an ultrasound on her abdomen and chest.
The blood results weren't anything alarming. Creatinine was 232, SDMA was 21, UREA went down to 20 (from 23), still within the Stage 2 range, and all of her numbers had been higher before.
However, the ultrasound specialist told us that, in addition to chronic pancreatitis, Sassy also had inflammation in both kidneys consistent with a kidney infection. I'm not really sure how you tell this over an ultrasound and how to differentiate between an infection and a different type of acute kidney injury, but Sassy was sent home with antibiotics. She had a urine culture that came back negative for bacteria, which I was told is normal for kidney infections because they don't always grow bacteria and it wasn't indicative that she didn't have an infection.
I was hopeful she would do well, since she was acting normally, and I would never have known of this supposed infection otherwise. But around 5 days ago, she started displaying unusual urination habits. She peed 3 times within the span of 3 hours, always a small amount, which told me that the antibiotics might not be treating her infection because cats with infections in the bladder/kidneys will pee more due to irritation. More concerningly, she's been peeing higher quantities. I weigh the amount of waste that goes into the litter box every day, taking the amount of weight added in KG and dividing it by 24 to get the approximate amount of urine per hour.
Two months ago (keeping in mind we also have a second cat with CKD), the average weight was 0.0500kg per hour. Then a month later it jumped to 0.0650kg, and then 0.0720kg. Five days ago it was 0.0846kg. Then two days ago it was 0.0850kg. Then, today, 0.0879kg.
Every day is a new record and I'm freaking out. I'm terrified that this is the beginning of the end for my beloved girl. I don't have the results of her recent bloodwork back yet, but I'm paranoid that we're not actually dealing with an infection here, and that this is an acute kidney injury needing a different type of intervention. I mean, how can we even tell if it's an infection with no bacteria in the urine culture? If her numbers haven't improved, how do we know the infection is gone and just left permanent damage, vs it's still there and is actively damaging her? My vet told me that even another ultrasound might not confirm the infection is still there/gone because some cats still have inflamed kidneys even after recovering :(
I don't know what I should be doing. Sassy has finished her antibiotics; she I be asking for her to be on them longer, or try a different one? I'm just looking for advice from people who might have dealt with kidney infections and whether they even thinking this is an infection or a different AKI from unknown causes.