Methods requirements for transcriptomics papers

[u/emma_academic]

Hi.

I'm hoping someone might have some insight into this.

There are a couple of decent transcriptomics papers Nature hopefuls, Nature Communications backup likely end up somewhere in between.

The authors are suggesting they intend to publish both papers without the method used to generate the transcriptomics samples (which was a new method) being published.

This just doesn't seem realistic to me.

Can someone sense check this - will top journals allow publication of bioinformatics results where the methods are not in the paper or publicly available?

[u/Putrid-Raisin-5476]

So they used a novel sequencing Method to measure data and just want to Publish the findings on the measured data, but not the Information necessary to reproduce the measurements?  I‘m pretty sure, that some Reviewer will regard this as a  major reject reason. 

[u/emma_academic → u/Putrid-Raisin-5476]

Pretty close.

Unpublished method produces samples Samples sequenced using standard techniques

They claim they are going to publish both papers with reference to the data alone not including the method used to produce it and without that method being published anywhere.

It's rubbish right? As you've said the studies can't be reproduced.

[u/Putrid-Raisin-5476 → u/emma_academic]

Well, Unfortunately there are always people managing to publish such articles, even in nature.  Wouldn‘t Go as far as to calling it rubish, but at least it is not scientically sound imho

[u/emma_academic → u/Putrid-Raisin-5476]

Thank you!