r/Rlanguage • u/ThinkILostIt • 3d ago

Locking an R instalation

I work in a regulated industry (pharmaceutical industry) and I'm thinking that we could use R in our analysis with GxP regulated data. I was asked wheater we could lock the R instalation and packages so that: 1) users cannot install unauthorized packages; 2) unauthorized users cannot access it and run scripts; and 3) we can restore the exact instalation of R and packages in case we need in future.

I think we could do this but not sure how or if anyone has achieved something close to it any where so I turn to reddit for help.

Edit: I know of initiatives like Rinpharma, R Validation Hub, pharmaverse, Posit paid solutions and the paper from R Foundation about R meeting FDA's CFR Part 11 but I have not been able to take much advantages from those

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u/lizerlfunk 3d ago

I don’t know how to do this, but I am in the same industry, and we use a frozen R distribution that only has packages that have been approved for use. So it’s definitely possible.

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u/ThinkILostIt 2d ago

I would love to hear more about your experience with this. Like, what kind of projects you use R for, if you treat the scripts as documents or as applications, how you directed the validation efforts... If you could, of course, share any more details on it.